The brainiacs at CERN are hoping to unlock more secrets of the universe with their third round of fun with the Large Hadron Collider.
That's right, the monster proton smasher is gearing up for another whirl-around.
And, with the Higgs-Boson particle already in the bag - some may know it as the God particle - scientists are keen to see what mysteries they'll uncover next.
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It's particularly timely as July 4 marked the 10th anniversary of the groundbreaking Higgs-Boson discovery.
Thousands of physicists work with the Large Hadron Collider CERN headquarters in Switzerland.
This time they're hoping to learn more about anti-matter this time. They're also hoping to uncover more about 'dark matter', according to SwissInfo.
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Dark matter is a type of matter that is currently invisible to scientific instruments so far developed. It is also thought to be more plentiful than conventional matter, and physicists are keen to learn more.
As well as exploring anti and dark matter, scientists will further delve into the Higgs-Boson particle.
Professor Daniela Bortoletto was on the team that confirmed its existence.
She explained why the God particle, a fundamental particle that gives mass to other subatomic components of the universe, was so sought-after.
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"The Higgs field explains why atoms exist, why we exist. And the fact that we can put it in a context that we think that we understand, I think is pretty cool," she told The Guardian.
Bortoletto also revealed what's next for the God particle.
"Understanding, for example, the Higgs self-coupling could [help us] understand the shape of the Higgs potential and understand better what happened at the beginning of the universe," Bortoletto said, as per The Guardian.
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She added: "There is a lot of scope in the Higgs sector. Again, we have a little bit more energy, we might discover something new, some new particle - we have a chance, every time we go higher in energy to discover maybe new physics."
This will be the first time the Large Hadron Collider has been booted up in three years.
Scientists shut down the massive particle smasher so they could work on the machine to improve its power and precision.
But as of Tuesday (July 5), some of the world's best and brightest minds will tinker with the very fabric of the universe to see what the Large Hadron Collider spits out.
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They hope for new discoveries now they have increased the energy, speed, and frequency of the protons ramming into each other inside the Collider.